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PENTEDRONE CRYSTAL, N-Ethyl-nor- pentedrone (also known as N-Ethylpentedrone, Ethyl-pentedrone or more commonly, NEP) is a lesser-known novel stimulant substance of the cathinone class that produces stimulating, euphoric, and mildly entactogenic effects when administered.
The stimulating effects of NEP are believed to mainly be caused by its activity as a norepinephrine-dopamine reuptake inhibitor (NDRI). The reported entactogenic effects it displays may also be due to its activity as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, although this has yet to be confirmed scientifically.
NEP shares a close structural relationship to its parent compound pentedrone, differing by an addition ethyl group on the terminal nitrogen on the carbon chain. This addition reportedly makes it about three times as potent as pentedrone. NEP is also closely related to N-Ethylhexedrone (commonly known as Hexen), and has been reported as producing largely-similar effects.
NEP first became known in the research chemical market during 2016. It is an example of a contemporary designer drug specifically chosen to mimic/replace the functional and structural features of its popular potent and short-lived-type stimulant predecessors, which are sometimes imprecisely referred to as “bath salts”.
As with its parent compound pentedrone, very little data exists about the pharmacological properties, metabolism, and toxicity of NEP in humans. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be treated with extreme caution. It is highly advised that one use harm reduction practices if choosing to use this substance.
Formal Name 2-(methylamino)-1-phenyl-1-pentanone, monohydrochloride
CAS Number 879669-95-1
Molecular Formula C12H17NO • HCl
Formula Weight 227.7
Formulation A neat solid
InChI Code InChI=1S/C12H17NO.ClH/c1-3-7-11(13-2)12(14)10-8-5-4-6-9-10;/h4-6,8-9,11,13H,3,7H2,1-2H3;1H
InChI Key MACVVBRQAPNUKT-UHFFFAOYSA-N
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